Observations on Conjugated and Unconjugated Blood Folate Levels in Megaloblastic Anemia and the Effects of Vitamin B 12.
نویسندگان
چکیده
منابع مشابه
Letter to the Editor
I enjoyed the article by 1. Eivazi Ziai, et al. concerning "Use of myeloperoxidase index as a suitable tool to monitor response to therapy in patients with megaloblastic anemia" that was published in the last issue of the Medical Journal ofIslamic Republic of Iran. I I would like to make some points regarding this study. A. The authors mentioned that in primary evaluation of 50 anemic pa...
متن کاملFolate deficiency associated with drug therapy for tuberculosis.
N ASSOCIATION BETWEEN megaloblastic anemia and therapy for tuberculosis has been described previously in five instances.1-3 In three patients megaloblastic erythropoiesis was associated with sideroblastic changes in the bone marrow,1’2 and in two the megaloblastic anemia was attributed .o deficiency of vitamin B12 resulting from malabsorption of this vitamin induced by therapy with para-amirios...
متن کاملApoptosis in megaloblastic anemia occurs during DNA synthesis by a p53-independent, nucleoside-reversible mechanism.
Deficiency of folate or vitamin B(12) (cobalamin) causes megaloblastic anemia, a disease characterized by pancytopenia due to the excessive apoptosis of hematopoietic progenitor cells. Clinical and experimental studies of megaloblastic anemia have demonstrated an impairment of DNA synthesis and repair in hematopoietic cells that is manifested by an increased percentage of cells in the DNA synth...
متن کاملPyrexia in a Patient with Megaloblastic Anemia: A Case Report and Literature Review
Deficiency of vitamin B12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. We aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin B12 and folate deficiency. The pyrexia subsided following the intramuscular injection of vitamin B12 and oral folic acid a...
متن کاملBeta-melanocyte stimulating hormone levels in subjects with hyperpigmentation associated with megaloblastic anemia.
By S. J. BAKER, V. I. MATHAN AND K. ABE H YPERPIGMENTATION OF THE SKIN in Indian patients with megaloblastic anemia appears to have been first documented by Cook.1 Studies from this unit suggested that this was often associated with vitamin B12 deficiency,2’3 though more recent studies following the introduction of folic acid assays, have shown that it can also occur in some cases of pure folat...
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ورودعنوان ژورنال:
- Blood
دوره 26 شماره
صفحات -
تاریخ انتشار 1965